I could see it being adapted to film (or even more ideally, made into a mini-series) more easily than I can see it being a play, which might strip it of too much context. The scenes are very lush and ornate and meticulously described throughout the book (which is a joy to read, btw; I did so back in the early 90s and read it over and over. And I'd read it again, even now).
Anna Karenina